https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:4594 Wed 11 Apr 2018 14:21:05 AEST ]]> DNA damage in human spermatozoa is highly correlated with the efficiency of chromatin remodeling and the formation of 8-hydroxy-2′-deoxyguanosine, a marker of oxidative stress https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8206 Sat 24 Mar 2018 08:36:17 AEDT ]]> Analysis of the relationships between oxidative stress, DNA damage and sperm vitality in a patient population: development of diagnostic criteria https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9572 Sat 24 Mar 2018 08:34:47 AEDT ]]> Comparison of intranasal and transcutaneous immunization for induction of protective immunity against Chlamydia muridarum respiratory tract infection https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:1210 TCI). Following in vitro re-stimulation of lung-draining lymph node cells with MOMP; IFNγ mRNA increased 20-fold in cells from IN immunized animals (compared to non-immunized controls) while IFNγ levels increased 6- to 7-fold in TCI animals. Ten days post challenge non-immunized animals had >7000 IFU in their lungs, IN immunized animals <50 IFU and TCI immunized animals <1500 IFU. Thus, both intranasal and transcutaneous immunization protected mice against respiratory challenge with Chlamydia. The best protection was obtained following IN immunization and correlated with IFNγ production by mononuclear cells in lung-draining LN and MOMP-specific IgA in BAL.]]> Sat 24 Mar 2018 08:28:39 AEDT ]]> Poly-immunoglobulin receptor-mediated transport of IgA into the male genital tract is important for clearance of chlamydia muridarum infection https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5204 Sat 24 Mar 2018 07:47:46 AEDT ]]>